Carcinogenic and mutagenic agents in the workplace, Poland, 2011–2012
نویسندگان
چکیده
منابع مشابه
Carcinogenic, teratogenic, and mutagenic effects of arsenic.
This review outlines briefly the history and present status of the problem of carcinogenic, teratogenic and mutagenic effects of arsenic. Discrepancies between clinical observations and positive results of epidemiological studies and the experimental induction of cancer by arsenic are discussed. The present knowledge of the mechanism of teratogenic and mutagenic effects of arsenic is analyzed. ...
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The mutagenic/carcinogenic activities of DEHP and MEHP were studied in bacteria and mammalian cells. MEHP but not DEHP exerted a dose-dependent DNA damaging effect to B. subtilis in Rec-assay. DEHP and MEHP showed mutagenic activities to S. typhimurium TA-100, with and without S-9 mix, respectively. MEHP produced not only the mutation in E. coli WP2B/r but also sister chromatid exchanges (SCE) ...
متن کاملThe Carcinogenic and Mutagenic Properties of TV-Hydroxy-aminonaphthalenes1'2
Af-Hydroxy-1-aminonaphthalene (JV-hydroxy-1-AN), N-hydroxy-2-aminonaphthalene (N-hydroxy-2-AN), 1-aminonaphthalene (1-AN), 2-aminonaphthalene (2-AN), and 2-amino1,4-naphthoquinone were repeatedly injected i.p. into rats at a dose of 5 mg/100 gm. Lower doses of 2-amino-l-naphthol (0.15 mg/100 gm), and of #-hydroxy-aniline (1.3 mg/100 gm) were also given i.p. ./V-Hydroxy-1-AN was a more potent ca...
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Many inhibitory and toxic effects show a dose dependence for which the extrapolation of a linear plot to zero or background effect cuts through the abscissa at some positive dose, indicating a threshold concentration below which the agent seems to be ineffective (1). If the teratogenic effect of such an agent is caused by the same cellular reaction, its dose-effect curve may also exhibit a thre...
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Numerous experimental observations have been made on microorganisms and culture of the cells of mammals as well as the accounting of the chromosomal aberrations in the bone marrow cells of the mammals and of human cells displayed that the chromium and its compounds possess a pronounced mutagenic effect. Translocation test, induction record of DNA damage and repair systems in the mammalian and h...
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ژورنال
عنوان ژورنال: Medycyna Pracy
سال: 2015
ISSN: 0465-5893
DOI: 10.13075/mp.5893.00181